After leaving their hometown of Royal Woods (setting of The Loud House), eleven-year old Ronnie Anne Santiago, her older brother Bobby, and their mother Maria move in with their extended family, the Casagrandes. The family includes Ronnie Anne's grandparents, Hector and Rosa; Aunt Frida and Uncle Carlos; cousins Carlota, CJ, Carl, Carlitos; and their pets, Sergio and Lalo.
Join Ronnie Anne's humorous adventures in her new home, Great Lake City, as she meets new friends and helps her grandpa run the family's mercado.